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In a November 2025 poll, one in eight American adults said they were currently taking a GLP1 drug

When combined with exercise, NNB's research shows that dihydroberberine supplementation led to powerful antioxidant effects: [2] A remarkable 34.2% decrease in Reactive Oxygen Species (ROS) compared to the exercise-only group Enhanced antioxidant enzyme activities , suggesting improved cellular protection against oxidative damage This reduction in oxidative stress is particularly noteworthy because elevated ROS levels are often associated with metabolic dysfunction and can impair athletic recovery

Most people experience significantly reduced appetite, making it easier to eat less without feeling deprived or constantly hungry

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