Decreased appetite: 16% While decreased appetite is technically listed as a side effect, it is also the primary therapeutic mechanism
Vascular risk factor variability and cognitive impairment in older adults a community-based retrospective study
Ron Grisanti, D.C., D.A.B.C.O., D.A.C.B.N., M.S., DIANM, CFMP Founder, Functional Medicine University Medical & Educational Disclaimer : The information provided is for educational purposes only and is not a substitute for personalized medical advice, diagnosis, or treatment
Additional risk factors include: Chronic kidney disease : Reduced renal clearance may impair B12 excretion Liver disease : Hepatic dysfunction can disrupt B12 metabolism and storage Myeloproliferative disorders : Certain blood cancers increase B12-binding proteins Concurrent medication use : Some drugs may interact with B12 metabolism, including metformin, proton pump inhibitors, and H2 antagonists Patients with these conditions should have B12 supplementation carefully monitored by their healthcare team