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However, this effect is short-lived, and as the body metabolises nicotine, it can result in a subsequent crash, leaving users feeling fatigued

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Brandt also attempts to trace the history of the cigarette to our identity as a culture, but here, as in so many places, he trips over a welter of nouns and compound phrases: "Resisting the blandishments of the companies and the addictiveness of nicotine is one cultural test of our discipline, independence, and individualism." Sentences like this made the book a real slog to get through

Uric acid has been shown to influence adipogenesis and fat accumulation, potentially exacerbating obesity in individuals with MetS